Prologue page 2, panel 6, taken directly from my roughs, with a tweak on the composition to mirror the previous image (John Cabot's voyage, Newfoundland 1497) slightly.
Through the second page of the Prologue we are introduced to the Hunters of the tribe and the idea of their supernatural abilities. The end shot shows the hunting Pack of four, transformed from Wolf to Human (hence their nakedness!) witnessing John Cabot's first few steps onto the island. Cabot's voyage marking the beginning of British colonization and nicely setting up where the main story starts 300 years later.